Rugiet Ready can interact with other medications you may be taking. Make sure to be honest and thorough with your doctor during the medical survey to avoid any adverse effects.
Medications containing any nitrates (such as nitroglycerin, isosorbide mononitrate or isosorbide dinitrate), nitrites or alkyl nitrites (also known as “poppers” or “rush”), as well as guanylate cyclase (GC) stimulators (such as riociguat or Adempas) must NOT be used at the same time as Rugiet Ready, as this combination may lead to a dangerous drop in blood pressure and/or syncope (fainting).
Revatio (sildenafil) is a medication prescribed for pulmonary hypertension. Do not take Rugiet Ready if you are prescribed Revatio (sildenafil)
Do not take with any illegal drugs.
AVOID grapefruit, grapefruit juice and excessive alcohol consumption when taking Rugiet Ready.
Use caution when taking Rugiet Ready with alpha-blockers or anti-hypertensive (blood pressure) medications, as this may lead to a drop in blood pressure and/or syncope (fainting).
Use caution when taking Rugiet Ready with strong CYP inhibitors (such as ritonavir, saquinavir, ketoconazole, itraconazole, erythromycin), as Rugiet Ready metabolism is decreased, and this may lead to a prolonged erection, a drop in blood pressure and/or syncope (fainting).
Rugiet Ready can interact with the following commonly prescribed medications. This is not an all-inclusive list. Be sure to include all medications that you take in the patient survey. If your medication list changes be sure to message your doctor.
Nitrate-containing medication
nitroglycerin (Gonitro, Nitrolingual, NitroMist, Nitrostat)
isosorbide mononitrade (Imdur, Ismo, Monoket)
isosorbite dinitrate (Dilatrate-SR, Isordil, Isordil Titradose)
nitrites or alkyl nitrites known as “poppers” or “rush”
Revatio (sildenafil)
Guanocyclase stimulators
riociguat (Adempas)
Alpha blockers
alfuzasin (Uroxatral)
doxazosin (Cadura)
dutasteride and tamulosin (Jalyn)
prazosin (Minipress)
silodosin (Rapaflo)
riociguat (Adempas)
terazosin (Hytrin)
Protease inhibitors
atazanavir (Reyataz)
darunavir (Prezista)
fosamprenavir (Lexiva)
indinavir (Crixivan)
lopinavir/ritonavir (Kaletra)
nelfinavir (Viracept)
ritonavir (Norvir)
saquinavir (Invirase)
tipranavir (Aptivus)
atazanavir/cobicistat (Evotaz)
darunavir/cobicistat (Prezcobix)
Antifungal medications
ketoconazole (Nizoral)
itraconazole (Sporanox)
Antibiotics
clarithromycin (Biaxin)
telithromycin (Ketek)
fosamprenavir (Lexiva)
All blood pressure medications can potentially cause a drop in blood pressure when used with Rugiet Ready and should be included in your medication list.