How long until I can wash the area or get wet? March 10, 2026 17:46 Updated Avoid showering, swimming or heavy sweating for two to four hours. This gives the medication time to absorb properly. Related articles How often do I apply the topical TRT? How long until the application site is safe for female or child exposure? What testosterone levels can I expect with injectable TRT? How often do I inject? What is meant by transference when someone applies topical testosterone?